Analytical Strategies for Green Extraction, Characterization, and Bioactive Evaluation of Polyphenols, Tocopherols, Carotenoids, and Fatty Acids in Agri-Food Bio-Residues

Vicente-Zurdo D. · Molecules · 2025 · 42 citations

What if the peels, seeds, and pulps you toss away could become the next superfood or life-saving medicine? A new review shows how cutting-edge green chemistry is turning agri-food waste into a treasure trove of bioactive compounds.

Forget landfill—agri-food bio-residues are the new gold mines. A comprehensive review highlights how these leftovers can be transformed into high-value compounds like polyphenols, tocopherols, carotenoids, and fatty acids, all through a biorefinery approach. This isn't just about waste management; it's about creating a circular economy where nothing goes to waste.

The key lies in green extraction technologies. The review examines supercritical fluid extraction, pressurized liquid extraction, pulsed electric fields, and matrix solid-phase dispersion. These methods promise better performance, lower energy use, and reduced costs—a win-win for the planet and industry.

Once extracted, accurate characterization is crucial. Spectrophotometric and high-resolution chromatographic techniques identify and quantify these bioactives with precision. Then, bioactivity assays reveal their potential: antioxidant, antimicrobial, anticancer, neuroprotective, and anti-inflammatory properties. These could revolutionize the food, pharmaceutical, and cosmetic sectors.

However, safety first: the review stresses the need to monitor toxic compounds like alkaloids in these residues. With careful control, this green approach paves the way for sustainable, eco-friendly industrial solutions.

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