Antibacterial and antifungal activities of natural deep eutectic solvents

As antibiotic resistance threatens global public health, science is turning its gaze toward an unexpected defender: customized liquid mixtures brewed from everyday natural components. Could the answer to escaping our microbial impasse be hiding in plain sight?

The relentless rise of antibiotic resistance has sparked an urgent global hunt for alternatives. Enter deep eutectic solvents—eco-friendly liquids boasting low volatility, minimal flammability, simple preparation, and wallet-friendly production costs. Beyond their usual day jobs in extracting biomolecules and formulating cosmetics, these solvents are stepping into the spotlight as formidable antimicrobial agents.

Taking sustainability a step further, researchers are looking at a specialized subclass: Natural Deep Eutectic Solvents, or NADES. Crafted entirely from natural sources through simple techniques like heating, stirring, grinding, or microwave-assisted synthesis, NADES perfectly match our modern push away from synthetic precursors.

This timely review dives into the untapped potential of NADES, charting their impressive antibacterial and antifungal capabilities. As conventional drugs lose their edge against stubborn pathogens, this groundbreaking literature survey lays the groundwork for a fresh, sustainable frontier in fighting microbial threats.

Key Points

• Natural deep eutectic solvents are promising antimicrobial alternative to antibiotics
• NADES holds high potential for their activity against bacterial resistance
• NADES have also substantial antifungal activities