Applications of (natural) deep eutectic solvents in liquid phase microextraction: A review

What if the secret to greener chemistry was hiding in plain sight, crafted from accessible, biodegradable ingredients? Meet Natural Deep Eutectic Solvents (NADES), the eco-friendly liquids transforming modern analytical chemistry.

Natural deep eutectic solvents are taking center stage as powerful green alternatives in analytical chemistry. Thanks to properties like high solubility, low volatility, low toxicity, and remarkable tunability, they are redefining how scientists approach liquid phase microextraction (LPME). When extracting delicate bioactive compounds from natural sources, NADES do the job brilliantly without damaging structural integrity or biological activity. Beyond extraction, these versatile solvents double as reaction catalysts and seamlessly integrate into chromatographic techniques for separating and analyzing natural compounds.

Researchers are particularly drawn to NADES for their impressive extraction efficiency, ability to stabilize analytes, and compatibility with detection methods. Because their components are readily available, easy to prepare, cost-effective, and biodegradable, they check every box for sustainable science.

Ultimately, harnessing NADES in sample preparation champions the core principles of green analytical chemistry. It is a smart, sustainable shift toward eco-friendly laboratory practices.

Key Points

• Green solvents with high solubility and low toxicity
• Efficient extraction without damaging bioactive compound structures
• Promotes sustainable and eco-friendly analytical chemistry practices