Combining the natural deep eutectic solvents and high-speed-shearing-enzymatic-assisted extraction to recover flavonoids and terpenoids from perilla leaves

Vo T.P. · Journal of Molecular Liquids · 2024 · 14 citations

What if the secret to unlocking nature's most valuable plant compounds was hiding in a simple, green solvent? A new study combines deep eutectic solvents with high-speed shearing and enzymes to recover flavonoids and terpenoids from perilla leaves—without the toxic chemicals.

Perilla leaves are a treasure chest of bioactive compounds, but traditional extraction methods often rely on harsh solvents. Researchers have now turned to Natural Deep Eutectic Solvents (NADES)—a new class of green solvents made from natural ingredients like sugars and organic acids. These solvents are not only eco-friendly but also highly effective at dissolving plant compounds.

The innovation doesn't stop there. By pairing NADES with high-speed-shearing and enzymatic assistance, the team accelerated the breakdown of plant cell walls. This triple-action approach boosts the release of flavonoids and terpenoids, two groups of compounds known for their antioxidant and anti-inflammatory properties.

The method is a step toward sustainable phytochemistry. It reduces reliance on petroleum-based solvents while improving extraction efficiency. For industries from cosmetics to pharmaceuticals, this could mean greener, cleaner production of plant-based ingredients.

The study demonstrates that combining physical, chemical, and biological tools can unlock nature's bounty with minimal environmental footprint. It's a win-win for science and the planet.

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