Comparative evaluation of ultrasound-assisted extraction and micelle-mediated extraction of bioactive compound from Acmella oleracea

Suktham K. · Scientific Reports · 2026 · 2 citations

What if the secret to unlocking a plant's healing power lies not in harsh chemicals, but in sound waves and tiny soap-like bubbles? A new study on Acmella oleracea—a flower known for its numbing effect—puts two green extraction methods head-to-head.

Acmella oleracea, a flower that tingles and numbs, is packed with bioactive compounds. But getting those compounds out efficiently and sustainably is a challenge. Researchers in Thailand and Malaysia compared two modern, eco-friendly techniques: ultrasound-assisted extraction and micelle-mediated extraction. Both aim to replace harsh solvents with gentler, greener alternatives. Ultrasound uses sound waves to burst plant cells, releasing their treasures. Micelles, on the other hand, are tiny molecular clusters that act like sponges, soaking up the target compounds. The study, published in Scientific Reports, evaluated which method yields more of the bioactive compounds. While the full results are pending final editing, the early findings offer a promising glimpse into more sustainable extraction. This research could transform how we source natural ingredients for medicine and cosmetics. The choice between sound and sponge may shape the future of green chemistry.

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