Edible Natural Deep Eutectic Solvents (NADESs)-Based Polyphenolic Extracts: An Eco-Sustainable Alternative for Grape Pomace Valorization

Roselli V. · Molecules · 2026 · 0 citations

What if the leftover grape skins from your favorite wine could become a treasure trove of health-boosting compounds—without a drop of toxic solvent? Scientists in Italy just turned that idea into a green reality.

Wine production leaves behind mountains of grape pomace—skins, seeds, and stems—often discarded as waste. But this "trash" is packed with polyphenols, natural antioxidants with huge potential for food and health industries. The challenge? Extracting them sustainably. Enter NADES, or natural deep eutectic solvents: eco-friendly liquids made from edible ingredients like betaine and lactic acid.

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