Green extraction and smart nanodelivery of bioactive molecules for industrial and biomedical applications

Thiruvengadam R. · Industrial Crops and Products · 2026 · 0 citations

What if the most powerful medicines on Earth were locked inside plants, waiting for a key? Green chemistry and tiny delivery vehicles might just be that key.

Plants are chemical factories, producing a treasure trove of bioactive molecules with therapeutic and functional promise. Yet, these compounds often suffer from poor solubility and low bioavailability, limiting their practical use. Enter green extraction technologies—like supercritical CO₂, ultrasound, and microwave-assisted methods—that efficiently harvest these delicate molecules without harsh solvents. But extraction is only half the battle. Nanotechnology provides the smart delivery systems: nanoencapsulation, nanoemulsions, biopolymer-based nanoparticles, and nanostructured lipid carriers. These tiny vehicles protect bioactives, improve their stability, and enable targeted delivery. Formulation techniques such as nanoprecipitation, spray drying, freeze drying, and layer-by-layer assembly fine-tune encapsulation efficiency, particle size, and shelf life. Together, green extraction and smart nanodelivery are unlocking the full potential of plant-derived compounds for food, pharmaceutical, cosmetic, and agricultural applications.

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