Green extraction of polyphenols from fruit waste using deep eutectic solvents and ultrasound-assisted techniques

Raj S.M. · Food Chemistry Advances · 2025 · 6 citations

What if fruit waste could become a treasure trove of health-boosting compounds? A new review shows how green chemistry turns trash into therapeutic gold.

Polyphenols are nature's multitaskers—antioxidant, anti-inflammatory, even cardioprotective. They're abundant in fruits and vegetables, but extracting them often relies on toxic solvents. This review explores a cleaner path: using Deep Eutectic Solvents (DES) and Ultrasound-Assisted Extraction (UAE) on fruit waste.

DES are eco-friendly solvents that selectively pull out bioactive compounds with high efficiency. When paired with UAE—which uses high-frequency sound waves to burst cell walls—the synergy is remarkable. The combination boosts yield, cuts processing time, and slashes solvent use, all while saving energy.

The review digs into key parameters like solvent type, temperature, and time, showing how they fine-tune extraction. The resulting polyphenols aren't just lab curiosities; they show promise for antioxidant activity and bioavailability. Potential applications span food, pharmaceuticals, and cosmetics, leveraging their natural preservative and therapeutic properties.

This isn't just about chemistry—it's about sustainability. By turning fruit waste into valuable compounds, we reduce waste and valorize natural resources. A win for science, industry, and the planet.

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