Microwave–Ultrasound-Assisted Extraction Coupled with Natural Deep Eutectic Solvent Enables High-Yield, Low-Solvent Recovery of Curcumin from Curcuma longa L.

Sahlan M. · Pharmaceutics · 2025 · 17 citations

Imagine getting more curcumin from turmeric while using half the solvent—this new method does exactly that, and it's faster and greener too.

Turmeric's golden compound, curcumin, is a powerhouse for health, but extracting it has always been a solvent-hungry process. Traditional methods demand large amounts of organic solvents, raising costs and environmental red flags. Now, researchers have found a smarter way: combining microwave and ultrasound with a natural deep eutectic solvent (NADES) made from choline chloride and lactic acid. This eco-friendly duo acts like a precision tool, breaking cell walls and dissolving curcumin efficiently without harsh chemicals.

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