NaDES Application in Cosmetic and Pharmaceutical Fields: An Overview

Villa C. · Gels · 2024 · 80 citations

Meet the green solvents quietly revolutionizing how we extract natural ingredients and deliver medicines. Natural deep eutectic solvents are proving that chemistry can be both powerful and eco-friendly.

Picture a solvent that is entirely non-flammable, surprisingly easy to prepare, and possesses an unexpected ability to dissolve lipophilic molecules—even though hydrophilic ones are mostly used. These are natural deep eutectic solvents, known as NaDES, emerging as a brilliant green alternative to traditional ionic liquids.

Thanks to their unique properties, NaDES are stepping into the spotlight for both cosmetic and pharmaceutical applications. They excel at sustainable extraction, yielding ready-to-use ingredients, and even paving the way for biocompatible, responsive drug delivery systems.

In the biomedical arena, these solvents double as biopolymer modifiers. Operating as therapeutic deep eutectic systems, they effortlessly solubilize and stabilize various chemical and galenical formulations.

This review maps out current knowledge to uncover fresh opportunities and challenges. The goal is to establish NaDES not just as green alternatives, but as vital pathways for delivering bioactive ingredients in breakthrough formulations.

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