Natural deep eutectic solvents providing enhanced stability of natural colorants from safflower

Dai, Y. et al. · Food Chemistry · 2014 · 400 citations

What happens when solid natural products melt into a liquid state just by mixing, creating a green solvent that protects fragile colors better than water or ethanol? Enter Natural Deep Eutectic Solvents.

When specific natural products are combined in a solid state, they magically turn into liquid. Known as Natural Deep Eutectic Solvents, or NADES, these eco-friendly liquids are making waves in foods, cosmetics, and pharmaceuticals. They dissolve tricky, water-insoluble compounds with ease, boasting wonderfully low toxicity. But their talents go beyond just dissolving things.

A new stability analysis reveals that natural pigments extracted from safflower thrive much better in sugar-based NADES than they do in standard water or a 40% ethanol solution. How do they pull this off? By reducing water content and ramping up viscosity, the stabilization capacity gets an extra boost.

This protective superpower comes down to chemistry: strong hydrogen bonding interactions form tightly between the solutes and the NADES molecules. Because they can shield phenolic compounds so effectively, these remarkable solvents hold brilliant promise for future applications across the food, cosmetic, and pharmaceutical industries.

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