Senise Red Pepper (Capsicum annuum L.) Wastes as Source of Rich Capsanthin Extracts by Supercritical CO2 Extraction

Larocca V. · Molecules · 2026 · 2 citations

What if pepper waste could paint your world with vibrant reds—and save the planet at the same time? A new study turns leftover Senise peppers into a treasure trove of natural pigments using nothing but pressurized CO2.

Every year, tons of pepper processing residues are tossed aside. But these scraps are far from worthless—they hide a rich cocktail of carotenoids, the natural compounds behind bright reds and oranges. Researchers zeroed in on Senise peppers, a sweet variety with Protected Geographical Indication (PGI) status, and tested a green extraction method using supercritical CO2.

In nine pressure–temperature combinations (250–450 bar, 40–60 °C, 60 minutes each), the team compared results to traditional solvent extraction. The yields were impressive: 21.5 to 23.5 grams per kilogram of dry weight. The best run—at 450 bar and 60 °C—recovered 70.2% of the carotenoids found by the solvent method, with a total carotenoid content of 386 mg per kilogram.

HPLC analysis revealed a colorful lineup: capsanthin dominated at 5.88 mg/g, followed by zeaxanthin, lutein, β-cryptoxanthin, β-carotene, and capsorubin. These are the very pigments that give red peppers their signature hue—and they're prized as natural colorants and antioxidants.

This isn't just about recycling waste; it's about turning a problem into a premium product. With supercritical CO2, we get clean, solvent-free extracts that could replace synthetic dyes in food and cosmetics. The future of color might just come from yesterday's pepper scraps.

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