Supercritical fluid extraction of bioactive compounds

da Silva R.P.F.F. · Trac Trends in Analytical Chemistry · 2016 · 646 citations

What if the ultimate green extraction method could capture nature's most valuable compounds without thermal degradation or messy solvents? The answer lies in the power of supercritical fluid technology.

An ideal extraction method must be swift, yield quantitative recovery without degradation, and easily separate extracts from the solvent. Traditional techniques often fall short, prompting scientists to seek alternative green technologies that improve efficiency while minimizing environmental impact.

Supercritical fluid technology steps up to this challenge, overcoming many limitations of conventional methods. This analytical overview explores how supercritical fluids are applied to extract valuable bioactive compounds, detailing the optimal operating conditions required for success.

Beyond basic extraction, the review investigates further technological advancements to boost efficiency, alongside experimental design strategies for optimization. Finally, it highlights the modern techniques used for the structural characterization and precise identification of these isolated bioactive molecules.

Key Points

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