The Extraction of Antioxidant Compounds from Coriandrum sativum Seeds by Using Green Solvents

What if the secret to a powerful antioxidant extraction lies in a simple, green solvent? Scientists have found a rapid, eco-friendly way to unlock the potential of coriander seeds using microwave assistance and natural deep eutectic solvents.

Coriander seeds are more than a kitchen staple—they're a treasure trove of bioactive compounds. But extracting those antioxidants often involves harsh chemicals. This study flips the script, using natural deep eutectic solvents (NADESs) as green alternatives, combined with microwave-assisted extraction (MAE) for speed and efficiency.

The team tested five different NADES formulations, pairing choline chloride with various hydrogen bond donors, including polyalcohols and organic acids. The winning combo? Choline chloride and 1,4-butanediol at a 1:4 molar ratio, which delivered the highest total antioxidant capacity (TAC). They measured antioxidant power using CUPRAC, DPPH, and ABTS assays, confirming the extracts' free radical scavenging prowess.

To optimize the process, response surface methodology (RSM) pinpointed the sweet spot: 326 watts of microwave power, 88 seconds of extraction time, and a 10:1 liquid-to-solid ratio. These conditions yielded maximum TAC, proving that green chemistry can be both effective and rapid.

This research offers an efficient, rapid, and environmentally friendly method to extract natural antioxidants from Turkish coriander seeds, opening doors for sustainable nutraceutical and food applications.

Key Points

• NADES + microwave extraction yields antioxidants from coriander seeds.
• Choline chloride/1,4-butanediol (1:4) is the best solvent.
• Optimal conditions: 326 W, 88 s, 10 L/S ratio.