The Most Potent Natural Pharmaceuticals, Cosmetics, and Food Ingredients Isolated from Plants with Deep Eutectic Solvents

Wawoczny A. · Journal of Agricultural and Food Chemistry · 2023 · 76 citations

Can we ditch synthetic chemicals and extract nature's most potent ingredients using purely eco-friendly tools? The answer lies in a revolutionary class of green solvents.

The pharmaceutical, cosmetic, and food industries are racing to replace synthetic additives with natural, plant-derived bioactive chemicals. But the real hurdle has always been finding an isolation method that is both efficient and genuinely ecological. Enter deep eutectic solvents—biodegradable, highly efficient extraction media that easily outperform traditional organic solvents while strictly adhering to the rules of green chemistry.

This review dives deep into modern, sustainable extraction methods using these remarkable solvents. It highlights recent breakthroughs in capturing valuable plant compounds like phenolics, flavonoids, terpenes, and saponins, while mapping out their biological activities and future applications.

Crucially, the research unpacks the vital factors driving extraction efficiency—such as water content, hydrogen bond donors and acceptors, and overall system design. It also tackles one of the field's biggest historical roadblocks: innovative new solutions for separating the solvents from the extract and making solvent recycling a reality.

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