The Optimum Condition Design of Microwave-assisted Extraction Combined Lactic Acid-Sucrose Based Natural Deep Eutectic Solvent on Polyphenols Enrichment from Eleutherine bulbosa Mill. Urb. Bulbs

Ahmad I. · Journal of Research in Pharmacy · 2023 · 4 citations

What if the key to unlocking nature's pharmacy lies in a solvent made from lactic acid and sugar, powered by microwaves? This study reveals the optimal conditions to enrich polyphenols from a medicinal bulb using a green, natural deep eutectic solvent.

Imagine a solvent that is not only green but also edible—a mix of lactic acid and sucrose, forming a natural deep eutectic solvent (NADES). Researchers are harnessing this eco-friendly liquid to extract polyphenols from the bulbs of Eleutherine bulbosa, a plant long used in traditional medicine. The challenge? Finding the perfect balance of extraction conditions to maximize yield without degrading the precious compounds.

This study zeroes in on microwave-assisted extraction, a technique that heats the solvent and plant material rapidly and uniformly. By tweaking parameters like microwave power, extraction time, and the ratio of solvent to raw material, the team aimed to design an optimum condition. The result? A method that not only boosts polyphenol recovery but also aligns with green chemistry principles, reducing energy and solvent waste.

The findings underscore the potential of NADES as a sustainable alternative to conventional organic solvents. With the right conditions, this approach could unlock the full therapeutic potential of Eleutherine bulbosa, paving the way for its use in nutraceuticals and pharmaceuticals. It's a small step for extraction science, but a giant leap for eco-conscious medicine.

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