Ultrasound-assisted extraction of phenolic compounds and antioxidant activities from Raphia farinifera Fruit: Box-Behnken design optimization and microstructural characterization

Djadou C. · Food Chemistry Advances · 2026 · 0 citations

Hidden inside a tropical fruit, a treasure trove of antioxidants awaits—and ultrasound is the key to unlocking it. Raphia farinifera, a local staple, reveals its potent phenolic riches when blasted with sound waves.

For centuries, locals have used Raphia farinifera fruits, yet their hidden chemistry remained a mystery. Now, scientists have turned to ultrasound—high-frequency sound waves—to coax out the fruit's bioactive compounds. Using a clever statistical tool called Box-Behnken design, they optimized four factors: time, temperature, ethanol concentration, and liquid-to-solid ratio.

The results were striking. The fruit's parts responded differently: the kernel boasted the highest phenolic content at 69.58 mg GAE/g DM, while the shell excelled in antioxidant activity with a 91.69% free radical scavenging rate. The pulp, though lower in phenolics, still showed impressive activity. Under a scanning electron microscope, the magic became visible: ultrasound created tiny pores in the plant cells, allowing solvents to penetrate deeper and wash out more compounds.

This green extraction method isn't just efficient—it's sustainable. The findings suggest Raphia farinifera extracts could shine in medicine, cosmetics, and food preservation. The fruit that nourished communities may soon nourish industries, all thanks to a little sonic help.

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